ea0037oc9.3 | Adrenal 2 | ECE2015
Debono Miguel
, Harrison Robert
, Keevil Brian
, Whitaker Martin
, Digweed Dena
, Arlt Wiebke
, Ross Richard
Introduction: Measuring serum cortisol to evaluate the normal circadian rhythm and adequacy of hydrocortisone replacement levels requires multiple readings; an expensive, cumbersome process. Conversely, salivary cortisone, a surrogate marker for free cortisol levels is non-invasive and well suited for out-patient settings. We hypothesised that salivary cortisone predicts circulating cortisol levels and can be used as an alternative marker of serum cortisol in a physiological s...